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Proteintech
ACD Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
25849-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ACD Fusion Protein Ag23021 (1-351 aa encoded by BC016904)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MPGRCQSDA AMRVNGPASR APAGWTSGSL HTGPRAGRPR AQARGVRGRG LLLRPRPAKE LPLPRKGGAW APAGNPGPLH PLGVAVGMAG SGRLVLRPWI RELILGSETP SSPRAGQLLE VLQDAEAAVA GPSHAPDTSD VGATLLVSDG THSVRCLVTR EALDTSDWEE KEFGFRGTEG RLLLLQDCGV HVQVAEGGAP AEFYLQVDRF SLLPTEQPRL RVPGCNQDLD VQKKLYDCLE EHLSESTSSN AGLSLSQLLD EMREDQEHQG ALVCLAESCL TLEGPCTAPP VTHWAASRCK ATGEAVYTVP SSMLCISEND QLILSSLGPC QRTQGPELPP PDPALQDLSL TL (1-351 aa encoded by BC016904)
靶标信息
This gene encodes a uridine 5' -monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5' -monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5' -monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: adrenocortical dysplasia homolog; POT1 and TIN2-interacting protein; TIN2 interacting protein 1; TPP 1; TPP I; TPPI; unnamed protein product
基因别名: DKCA6; DKCB7; PIP1; PTOP; TINT1; TPP1
UniProt ID: (Human) Q96AP0
Entrez Gene ID: (Human) 65057
telomere maintenance
intracellular protein transport
telomere maintenance via telomerase
telomere capping
protection from non-homologous end joining at telomere
telomere assembly
positive regulation of telomere maintenance
negative regulation of telomere maintenance via telomerase
protein localization to chromosome, telomeric region
establishment of protein localization to telomere
regulation of establishment of protein localization to telomere
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