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Proteintech
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Immunogen sequence: MPGRCQSDA AMRVNGPASR APAGWTSGSL HTGPRAGRPR AQARGVRGRG LLLRPRPAKE LPLPRKGGAW APAGNPGPLH PLGVAVGMAG SGRLVLRPWI RELILGSETP SSPRAGQLLE VLQDAEAAVA GPSHAPDTSD VGATLLVSDG THSVRCLVTR EALDTSDWEE KEFGFRGTEG RLLLLQDCGV HVQVAEGGAP AEFYLQVDRF SLLPTEQPRL RVPGCNQDLD VQKKLYDCLE EHLSESTSSN AGLSLSQLLD EMREDQEHQG ALVCLAESCL TLEGPCTAPP VTHWAASRCK ATGEAVYTVP SSMLCISEND QLILSSLGPC QRTQGPELPP PDPALQDLSL TL (1-351 aa encoded by BC016904)
This gene encodes a uridine 5' -monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5' -monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5' -monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ACCELERATED CELL DEATH 2; adrenocortical dysplasia homolog; Adrenocortical dysplasia protein homolog; AP22.36; AP22_36; ARABIDOPSIS THALIANA RED CHLOROPHYLL CATABOLITE REDUCTASE; AT4G37000; ATRCCR; POT1 and TIN2-interacting protein; RCCR; RED CHLOROPHYLL CATABOLITE REDUCTASE; TIN2 interacting protein 1; TPP 1; TPP I; TPPI; unnamed protein product
基因别名: ACD; DKCA6; DKCB7; PIP1; PTOP; TINT1; TPP1
UniProt ID: (Human) Q96AP0
Entrez Gene ID: (Human) 65057