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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKGATTNICY NVLDRNVHEK KLGDKVAFYW EGNEPGETTQ ITYHQLLVQV CQFSNVLRKQ GIQKGDRVAI YMPMIPELVV AMLACARIGA LHSIVFAGFS SESLCERILD SSCSLLITTD AFYRGEKLVN LKELADEALQ KCQEKGFPVR CCIVVKHLGR AELGMGDSTS QSPPIKRSCP DVQISWNQGI DLWWHELMQE AGDECEPEWC DAEDPLFILY TSGSTGKPKG VVHTVGGYML YVATTFKYVF DFHAEDVFWC TADIGWITGH SYVTYGPLAN GATSVLFEGI PTYPDVNRLW SIVDKYKVTK FYTAPTAIRL LMKFGDEPVT KHSRASLQVL GTVGEPINPE AWLWYHRVVG AQRCPIVDTF WQTETGGHML TPLPGATPMK PGSATFPFFG VAPAILNESG EELEGEAEGY LVFKQPWPGI MRTVYGNHER FETTYFKKFP GYYVTGDGCQ RDQDGYYWIT GRIDDMLNVS GHLLSTAEVE SALVEHEAVA EAAVVGHPHP VKGECLYCFV TLCDGHTFSP KLTEELKKQI REKIGPIATP DYIQNAPGLP KTRSGKIMRR VLRKIAQNDH DLGDMSTVAD PSVISHLFSH RCLTIQ
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AceCS1; Acetate--CoA ligase; Acetyl-CoA synthetase; Acetyl-CoA synthetase 1; Acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acyl-activating enzyme; Acyl-CoA synthetase short-chain family member 2; Propionate--CoA ligase
基因别名: ACAS2; ACSS2
Entrez Gene ID: (Human) 55902