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PA1-29875 detects ACTH from human, mouse, and rat samples.
PA1-29875 has been successfully used in immunocytochemistry, and Western blot applications. Predicted molecular weight of 29 kDa.
The PA1-29875 immunogen is recombinant fragment, corresponding to amino acids 6-266 of Human ACTH.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thawe cycles.
ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。