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PA5-16837 targets Adrenocorticotrophic Hormone in WB applications and shows reactivity with Human and Many samples.
The PA5-16837 immunogen is synthetic peptide derived from N-terminus of human ACTH.
ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。