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Proteintech
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Immunogen sequence: MESYDIIAN QPVVIDNGSG VIKAGFAGDQ IPKYCFPNYV GRPKHMRVMA GALEGDLFIG PKAEEHRGLL TIRYPMEHGV VRDWNDMERI WQYVYSKDQL QTFSEEHPVL LTEAPLNPSK NREKAAEVFF ETFNVPALFI SMQAVLSLYA TGRTTGVVLD SGDGVTHAVP IYEGFAMPHS IMRVDIAGRD VSRYLRLLLR KEGVDFHTSA EFEVVRTIKE RACYLSINPQ KDEALETEKV QYTLPDGSTL DVGPARFRAP ELLFQPDLVG DESEGLHEVV AFAIHKSDMD LRRTLFANIV LSGGSTLFKG FGDRLLSEVK KLAPKDIKIK ISAPQERLYS TWIGGSILAS LDTFKKMWVS KKEYEEDGSR AIHRKTF (1-376 aa encoded by BC010090)
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Actin-related protein 1B; ARP1; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1B; Beta-centractin; centractin beta; yeast homolog B
基因别名: 2310066K23Rik; AA960180; ACTR1B; AI851923; ARP1B; CTRN2; PC3
UniProt ID: (Human) P42025, (Mouse) Q8R5C5
Entrez Gene ID: (Human) 10120, (Rat) 316333, (Mouse) 226977