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Invitrogen
ADAMTS1 Polyclonal Antibody
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ADAMTS1 Antibody (720329) in WB
Western blot analysis was performed on Whole cell extracts (30 µg lysate) of HeLa (Lane 1), U-87 MG (Lane 2), PC-3 (Lane 3), NTERA-2 (Lane 4) and tissue extracts of Mouse Liver (Lane 5). The blots were probed with Anti-ADAMTS-1 Rabbit Polyclonal Antibody (Product # 720329, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 61 kDa band corresponding to ADAMTS-1 was observed across the cell lines and tissues test... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
720329
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptides corresponding to Human ADAMTS1 (aa 337-351, 465-479)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.1% BSA, 30% glycerol
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Pig and Sheep
靶标信息
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: a disintegrin and metalloproteinase; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM-TS 1; ADAM-TS1; ADAMs; ADAMTS-1; ADAMTS1; extracellular protein with metalloprotease and TSP domains; human metalloproteinase with thrombospondin type 1 motifs; metalloendopeptidases; metalloprotease and thrombospondin-1; METH-1; unnamed protein product
基因别名: ADAM-TS1; ADAMTS; ADAMTS-1; C3-C5; METH-1; METH1
UniProt ID: (Human) Q9UHI8, (Mouse) P97857
Entrez Gene ID: (Human) 9510, (Mouse) 11504
proteolysis
integrin-mediated signaling pathway
negative regulation of cell proliferation
negative regulation of angiogenesis
extracellular matrix organization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
ovulation from ovarian follicle
kidney development
positive regulation of neuron projection development
heart trabecula formation
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