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Invitrogen
ADAMTSL1 Monoclonal Antibody (1B2-8-14)
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产品信息
MA5-33369
产品规格
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
1B2-8-14
偶联物
形式
Liquid
浓度
100 µg/mL
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Product is supplied at 1 mL (100 µL/mL). This antibody recognizes the spacer domain and reacts with molecular species of 55 kDa or a doublet of 55 kDa and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.
Western blotting applications the antibody works better in non-reducing than reducing conditions although it will also recognize the reduced antigen at correspondingly higher concentrations.
靶标信息
Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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