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Invitrogen
ADH4 Polyclonal Antibody
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产品信息
PA5-95375
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human ADH4 recombinant protein (Position: K218-F380).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Human ADH4 shares 68.7% and 71.8% amino acid (aa) sequence identity with mouse and rat ADH4, respectively.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat liver tissue, mouse liver tissueHEPG2 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADH2; Alcohol dehydrogenase 2; Alcohol dehydrogenase 4; Alcohol dehydrogenase class II; Alcohol dehydrogenase class II pi chain; Alcohol dehydrogenase II; aldehyde reductase; All-trans-retinol dehydrogenase [NAD(+)] ADH4; class II alcohol dehydrogenase, pi subunit; class II type ADH; epididymis secretory protein Li 4
基因别名: Ac1002; ADH-1; ADH-2; ADH2; ADH4; HEL-S-4
UniProt ID: (Human) P08319, (Mouse) Q9QYY9
Entrez Gene ID: (Human) 127, (Mouse) 26876, (Rat) 29646
NADPH:quinone reductase activity
alcohol dehydrogenase (NAD) activity
alcohol dehydrogenase activity, zinc-dependent
alditol:NADP+ 1-oxidoreductase activity
retinol dehydrogenase activity
all-trans retinal binding
zinc ion binding
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
benzaldehyde dehydrogenase activity
retinol binding
ethanol binding
NAD binding
oxidoreductase activity
metal ion binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
