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Invitrogen
ADORA2B Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-72850
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 19 amino acid peptide near the carboxy terminus of human ADORA2B, located within the last 50 amino acids.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
ADORA2B encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: A2b receptor; A2b, Rs; HGNC:264; netrin-1 receptor; unnamed protein product
基因别名: A2b; A2BAR; A2BR; AA2BR; ADORA2; ARA2B
UniProt ID: (Human) P29275, (Mouse) Q60614, (Rat) P29276
Entrez Gene ID: (Human) 136, (Mouse) 11541, (Rat) 29316
positive regulation of endothelial cell proliferation
adenosine receptor signaling pathway
positive regulation of chronic inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of endothelial cell migration
regulation of cell communication
positive regulation of norepinephrine secretion
positive regulation of steroid biosynthetic process
regulation of glucose metabolic process
regulation of signaling
positive regulation of guanylate cyclase activity
positive regulation of chemokine production
positive regulation of interleukin-6 production
negative regulation of collagen biosynthetic process
positive regulation of catecholamine secretion
vasodilation
positive regulation of mast cell degranulation
relaxation of vascular smooth muscle
presynaptic modulation of chemical synaptic transmission
positive regulation of cAMP/PKA signal transduction
response to angiotensin
regulation of amine transport
regulation of secretion by cell
activation of adenylate cyclase activity
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