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Proteintech
AFG3L2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
14631-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AFG3L2 Fusion Protein Ag6209 (449-797 aa encoded by BC065016)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.36 mg/mL
规格
54 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ILAGTNRPD ILDPALLRPG RFDRQIFIGP PDIKGRASIF KVHLRPLKLD STLEKDKLAR KLASLTPGFS GADVANVCNE AALIAARHLS DSINQKHFEQ AIERVIGGLE KKTQVLQPEE KKTVAYHEAG HAVAGWYLEH ADPLLKVSII PRGKGLGYAQ YLPKEQYLYT KEQLLDRMCM TLGGRVSEEI FFGRITTGAQ DDLRKVTQSA YAQIVQFGMN EKVGQISFDL PRQGDMVLEK PYSEATARLI DDEVRILIND AYKRTVALLT EKKADVEKVA LLLLEKEVLD KNDMVELLGP RPFAEKSTYE EFVEGTGSLD EDTSLPEGLK DWNKEREKEK EEPPGEKVAN (449-797 aa encoded by BC065016)
靶标信息
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AFG3 (ATPase family gene 3)-like 2; AFG3 ATPase family gene 3-like 2; AFG3 ATPase family member 3-like 2; AFG3 like AAA ATPase 2; AFG3-like AAA ATPase 2; AFG3-like protein 2; ATPase family gene 3, yeast; FLJ25993; paraplegin-like protein; unnamed protein product
基因别名: 2310036I02Rik; Emv66; OPA12; par; SCA28; SPAX5
UniProt ID: (Human) Q9Y4W6, (Mouse) Q8JZQ2
Entrez Gene ID: (Human) 10939, (Rat) 307350, (Mouse) 69597
proteolysis
mitochondrion organization
axonogenesis
neuromuscular junction development
mitochondrial fusion
biological_process
protein processing
protein autoprocessing
nerve development
protein catabolic process
membrane protein proteolysis
mitochondrial protein processing
calcium ion transmembrane import into mitochondrion
regulation of multicellular organism growth
cristae formation
myelination
mitochondrial calcium ion homeostasis
protein maturation
muscle cell development
righting reflex
cellular response to glutathione
regulation of calcium import into the mitochondrion
mitochondrial protein quality control
glutathione import into mitochondrion
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