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Invitrogen
AGTR1 (extracellular) Polyclonal Antibody
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AGTR1 (extracellular) Antibody (PA5-77280) in ICC/IF
Immunocytochemistry analysis of AGTR1 (extracellular) in rat C6 glioma cells. A) Samples were probed with AGTR1 (extracellular) polyclonal antibody (Product # PA5-77280) at a dilution of 1:100, and incubated with goat anti-rabbit-AlexaFluor-555. B) Live view cell image.
产品信息
PA5-77280
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide NSSTEDGIKRIQDDC, corresponding to amino acid residues 4-18 of human AT1 receptor
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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