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Invitrogen
AGTR2 (extracellular) Polyclonal Antibody
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AGTR2 (extracellular) Antibody (PA5-77281) in ICC/IF
Immunocytochemistry analysis of AGTR2 (extracellular) in rat pituitary cells. Samples were probed with AGTR2 (extracellular) polyclonal antibody (Product # PA5-77281) at a dilution of 1:100, and incubated with goat anti-rabbit-AlexaFluor-555.
产品信息
PA5-77281
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide DNLNATGTNESAFNC, corresponding to amino acid residues 21-35 of rat AT2 Receptor
偶联物
形式
Lyophilized
浓度
0.4 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.
Reconstitute using 50 uL deionized water.
靶标信息
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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