Abnova

AKAP13 Polyclonal Antibody, MaxPab™

Name: AKAP13 Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00011214-B01P

查看其他10个AKAP13抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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AKAP13 Antibody (H00011214-B01P) in WB

Western Blot analysis of AKAP13 expression in transfected 293T cell line by AKAP13 MaxPab polyclonal antibody. Lane 1: AKAP13 transfected lysate(116.38 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00011214-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

AKAP13 (NP_658913.1, 1 a.a. approximately 1058 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MSSSKKSKEK EKEKDKIKEK EKDSKDKEKD KKTVNGHTFS SIPVVGPISC SQCMKPFTNK DAYTCANCSA FVHKGCRESL ASCAKVKMKQ PKGSLQAHDT SSLPTVIMRN KPSQPKERPR SAVLLVDETA TTPIFANRRS QQSVSLSKSV SIQNITGVGN DENMSNTWKF LSHSTDSLNK ISKVNESTES LTDEGVGTDM NEGQLLGDFE IESKQLEAES WSRIIDSKFL KQQKKDVVKR QEVIYELMQT EFHHVRTLKI MSGVYSQGMM ADLLFEQQMV EKLFPCLDEL ISIHSQFFQR ILERKKESLV DKSEKNFLIK RIGDVLVNQF SGENAERLKK TYGKFCGQHN QSVNYFKDLY AKDKRFQAFV KKKMSSSVVR RLGIPECILL VTQRITKYPV LFQRILQCTK DNEVEQEDLA QSLSLVKDVI GAVDSKVASY EKKVRLNEIY TKTDSKSIMR MKSGQMFAKE DLKRKKLVRD GSVFLKNAAG RLKEVQAVLL TDILVFLQEK DQKYIFASLD QKSTVISLKK LIVREVAHEE KGLFLISMGM TDPEMVEVHA SSKEERNSWI QIIQDTINTL NRDEDEGIPS ENEEEKKMLD TRARELKEQL HQKDQKILLL LEEKEMIFRD MAECSTPLPE DCSPTHSPRV LFRSNTEEAL KGGPLMKSAI NEVEILQGLV SGNLGGTLGP TVSSPIEQDV VGPVSLPRRA ETFGGFDSHQ MNASKGGEKE EGDDGQDLRR TESDSGLKKG GNANLVFMLK RNSEQVVQSV VHLYELLSAL QGVVLQQDSY IEDQKLVLSE RALTRSLSRP SSLIEQEKQR SLEKQRQDLA NLQKQQAQYL EEKRRREREW EARERELRER EALLAQREEE VQQGQQDLEK EREELQQKKG TYQYDLERLR AAQKQLEREQ EQLRREAERL SQRQTERDLC QVSHPHTKLM RIPSFFPSPE EPPSPSAPSI AKSGSLDSEL SVSPKRNSIS RTHKDKGPFH ILSSTSQTNK GPEGQSQAPA STSASTRLFG LTKPKEKKEK KKKNKTSRSQ PGDGPASEVS AEGEEIFC

靶标信息

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: A kinase (PRKA) anchor protein 13; A-kinase anchor protein 13; A-kinase anchoring protein; AKAP-13; AKAP-Lbc; Breast cancer nuclear receptor-binding auxiliary protein; Guanine nucleotide exchange factor Lbc; Human thyroid-anchoring protein 31; LBC oncogene; Lymphoid blast crisis oncogene; Non-oncogenic Rho GTPase-specific GTP exchange factor; p47; PRKA13; Protein kinase A-anchoring protein 13

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基因别名: AKAP-13; AKAP-Lbc; AKAP13; ARHGEF13; BRX; c-lbc; HA-3; HT31; LBC; p47; PRKA13; PROTO-LB; PROTO-LBC

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UniProt ID: (Human) Q12802

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Entrez Gene ID: (Human) 11214

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功能