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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: NNNPYGNGTA IFTTNGATAR KYAHLVDVGQ VGVNVPIPVP LPMFSFTGSR SSFRGDTNFY GKQGIQFYTQ LKTITSQWKE EDATLSSPAV VMP
Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 97%.
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Aldehyde dehydrogenase family 6 member A1; Malonate-semialdehyde dehydrogenase [acylating]; Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; MMSDH
基因别名: ALDH6A1; MMSDH
Entrez Gene ID: (Human) 4329