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Proteintech
ALOX15 Polyclonal Antibody
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产品信息
13286-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ALOX15 fusion protein Ag4040
偶联物
形式
Liquid
浓度
400 µg/mL
规格
60 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: MGLYRIRVST GASLYAGSNN QVQLWLVGQH GEAALGKRLW PARGKETELK VEVPEYLGPL LFVKLRKRHL LKDDAWFCNW ISVQGPGAGD EVRFPCYRWV EGNGVLSLPE GTGRTVGEDP QGLFQKHREE ELEERRKLYR WGNWKDGLIL NMAGAKLYDL PVDERFLEDK RVDFEVSLAK GLADLAIKDS LNVLTCWKDL DDFNRIFWCG QSKLAERVRD SWKEDALFGY QFLNGANPVV LRRSAHLPAR LVFPPGMEEL QAQLEKELEG GTLFEADFSL LDGIKANVIL CSQQHLAAPL VMLKLQPDGK LLPMVIQLQL PRTGSPPPPL FLPTDPPMAW LLAKCWVRSS DFQ
靶标信息
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 12-LOX; 12/15-lipoxygenase; 12/15-LO; 12/15-LOX; 15-lipooxygenase-1; 15-lipoxygenase; 15-lipoxygenase type 1; 15-LOX; 15-LOX type 1; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15; unnamed protein product
基因别名: 12-LO; 12-LOX; 12/15-LO; 15-LOX; 15-LOX-1; Alox12; Alox12l; ALOX15; L-12LO; LOG15
UniProt ID: (Human) P16050, (Mouse) P39654, (Rat) Q02759
Entrez Gene ID: (Human) 246, (Mouse) 11687, (Rat) 81639
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
lipid binding
linoleate 13S-lipoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
arachidonate 15-lipoxygenase activity
dioxygenase activity
hepoxilin-epoxide hydrolase activity
hepoxilin A3 synthase activity
potassium channel inhibitor activity
oxygenase
ossification
negative regulation of adaptive immune response
lipid metabolic process
fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
bone mineralization
positive regulation of actin filament polymerization
lipid oxidation
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
long-chain fatty acid biosynthetic process
apoptotic cell clearance
linoleic acid metabolic process
regulation of inflammatory response
hepoxilin biosynthetic process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process
positive regulation of heterotypic cell-cell adhesion
oxidation-reduction process
positive regulation of cell proliferation
positive regulation of cell growth
regulation of membrane potential
negative regulation of apoptotic process
negative regulation of cell volume
icosanoid biosynthetic process
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