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Proteintech
AMH Polyclonal Antibody, CoraLite® Plus 488
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产品信息
CL488-14461
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AMH fusion protein Ag5670
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: GLALTLQPR GEDSRLSTAR LQALLFGDDH RCFTRMTPAL LLLPRSEPAP LPAHGQLDTV PFPPPRPSAE LEESPPSADP FLETLTRLVR ALRVPPARAS APRLALDPDA LAGFPQGLVN LSDPAALERL LDGEEPLLLL LRPTAATTGD PAPLHDPTSA PWATALARRV AAELQAAAAE LRSLPGLPPA TAPLLARLLA LCPGGPGGLG DPLRALLLLK ALQGLRVEWR GRDPRGPGRA QRSAGATAAD GPCALRELSV DLRAERSVLI PETYQANNCQ GVCGWPQSDR NPRYGNHVVL LLKMQARGAA LARPPCCVPT AYAGKLLISL SEERISAHHV PNMVATECGC R
靶标信息
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AMH; Anti - Mullerian hormone (Mulerian inhibiting substance); Anti-Muellerian hormone; MIS; Muellerian-inhibiting factor; Muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
基因别名: AMH; MIF; MIS
UniProt ID: (Human) P03971, (Rat) P49000, (Mouse) P27106
Entrez Gene ID: (Human) 268, (Rat) 25378, (Mouse) 11705
preantral ovarian follicle growth
urogenital system development
Mullerian duct regression
cell-cell signaling
gonadal mesoderm development
aging
positive regulation of gene expression
response to organic cyclic compound
response to drug
positive regulation of NF-kappaB transcription factor activity
negative regulation of ovarian follicle development
sex determination
sex differentiation
