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OriGene
AMH Recombinant Rabbit Monoclonal Antibody (OTIR5D9), TrueRAB™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
TA600549
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
OTIR5D9
抗原
Recombinant protein (26-560aa) of human AMH produced in HEK293
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Dilute in PBS (pH7.3) if necessary. Stable for 12 months from date of receipt.
靶标信息
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: muellerian-inhibiting factor; muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
基因别名: MIF; MIS
UniProt ID: (Human) P03971
Entrez Gene ID: (Human) 268
ovarian follicle development
preantral ovarian follicle growth
Mullerian duct regression
cell-cell signaling
sex determination
sex differentiation
gonad development
response to xenobiotic stimulus
positive regulation of gene expression
Leydig cell differentiation
development of primary male sexual characteristics
positive regulation of SMAD protein import into nucleus
anti-Mullerian hormone signaling pathway
negative regulation of ovarian follicle development
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