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Invitrogen
AMOTL2 Polyclonal Antibody
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AMOTL2 Antibody (PA5-78495) in ICC/IF
AMOTL2 Polyclonal Antibody detects AMOTL2 protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: AMOTL2 protein stained by AMOTL2 Polyclonal Antibody (Product # PA5-78495) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-78495
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human AMOTL2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted Reactivity: Mouse (93%), Rat (92%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Angiomotin-like protein 2; LCCP; Leman coiled-coil protein
基因别名: AMOTL2; KIAA0989; LCCP
UniProt ID: (Human) Q9Y2J4
Entrez Gene ID: (Human) 51421
