Proteintech

ANAPC5 Polyclonal Antibody

Name: ANAPC5 Polyclonal Antibody
Brand: Proteintech
SKU: 14926-1-AP

查看其他8个APC5抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (7)

ANAPC5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ANAPC5 Antibody (14926-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using (Product # 14926-1-AP) (ANAPC5 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Immunogen image

Immunogen Image ANAPC5 Polyclonal Antibody

产品信息

14926-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:20-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ANAPC5 Fusion Protein Ag6688 (1-343 aa encoded by BC001081)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.19 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MASVHESLY FNPMMTNGVV HANVFGIKDW VTPYKIAVLV LLNEMSRTGE GAVSLMERRR LNQLLLPLLQ GPDITLSKLY KLIEESCPQL ANSVQIRIKL MAEGELKDME QFFDDLSDSF SGTEPEVHKT SVVGLFLRHM ILAYSKLSFS QVFKLYTALQ QYFQNGEKKT VEDADMELTS RDEGERKMEK EELDVSVREE EVSCSGPLSQ KQAEFFLSQQ ASLLKNDETK ALTPASLQKE LNNLLKFNPD FAEAHYLSYL NNLRVQDVFS STHSLLHYFD RLILTGAESK SNGEEGYGRS LRYAALNLAA LHCRFGHYQQ AELALQEAIR IAQESNDHVC LQHC (1-343 aa encoded by BC001081)

靶标信息

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome, a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein, compared to isoform a.

仅用于科研。不用于诊断过程。未经明确授权不得转售。