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Proteintech
ANGPTL4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
18374-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ANGPTL4 Fusion Protein Ag13237 (1-374 aa encoded by BC023647)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.29 mg/mL
规格
43.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSGAPTAGA ALMLCAATAV LLSAQGGPVQ SKSPRFASWD EMNVLAHGLL QLGQGLREHA ERTRSQLSAL ERRLSACGSA CQGTEGSTDL PLAPESRVDP EVLHSLQTQL KAQNSRIQQL FHKVAQQQRH LEKQHLRIQH LQSQFGLLDH KHLDHEVAKP ARRKRLPEMA QPVDPAHNVS RLHRLPRDCQ ELFQVGERQS GLFEIQPQGS PPFLVNCKMT SDGGWTVIQR RHDGSVDFNR PWEAYKAGFG DPHGEFWLGL EKVHSITGDR NSRLAVQLRD WDGNAELLQF SVHLGGEDTA YSLQLTAPVA GQLGATTVPP SGLSVPFSTW DQDHDLRRDK NCAKSLSGGW WFGTCSHSNL NGQYFRSIPQ QRQKL (1-374 aa encoded by BC023647)
靶标信息
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 425O18-1; angiopoietin-like protein 4; ANGPTL2; contains fibrinogen-like domain; Fasting-i; fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; hepatic angiopoietin-related protein; hepatic fibrinogen/angiopoietin-related protein; major histocompatibility complex region NG27; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PPARG angiopoietin related protein; secreted protein; secreted protein Bk89; unnamed protein product
基因别名: ARP4; Bk89; FIAF; HARP; HFARP; Ng27; NL2; PGAR; Pgarg; Pp1158; TGQTL; UNQ171
UniProt ID: (Human) Q9BY76, (Mouse) Q9Z1P8
Entrez Gene ID: (Human) 51129, (Mouse) 57875
response to hypoxia
blood coagulation
negative regulation of very-low-density lipoprotein particle remodeling
negative regulation of apoptotic process
protein unfolding
negative regulation of fatty acid biosynthetic process
positive regulation of angiogenesis
positive regulation of multicellular organismal process
triglyceride homeostasis
regulation of chylomicron remodeling
regulation of triglyceride transport
cellular response to starvation
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
negative regulation of endothelial cell apoptotic process
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