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Invitrogen
ANKH Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-66977
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ACYVYRKQKKK MENESATEGE DSAMTDMPPT EEVTDIVEMR EENE
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 98%.
靶标信息
ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ankylosis, progressive homolog; ATP carrier protein ANKH; FLJ27166; progressive ankylosis protein homolog; solute carrier family 62, member 1; unnamed protein product
基因别名: ANK; CCAL2; CMDJ; CPPDD; HANK; MANK; SLC62A1
UniProt ID: (Human) Q9HCJ1
Entrez Gene ID: (Human) 56172
skeletal system development
locomotory behavior
gene expression
bone mineralization
regulation of bone mineralization
inorganic diphosphate transport
phosphate ion transmembrane transport
phosphate ion homeostasis
calcium ion homeostasis
transmembrane transport
diphosphate metabolic process
cementum mineralization
inhibition of non-skeletal tissue mineralization
response to sodium phosphate
ATP export
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