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Invitrogen
ANKRD26P1 Recombinant Mouse Monoclonal Antibody (K40073_16B3)
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ANKRD26P1 Antibody (MA564426) in IHC (P)
Immunohistochemistry (Paraffin) analysis of ANKRD26P1 in formalin-fixed paraffin-embedded testis tissue. Samples were incubated with ANKRD26P1 recombinant monoclonal (Product # MA564426) using a dilution of 4.9 µg/mL at room temperature for 1 hr followed by Poly-peroxidase conjugated goat anti-mouse IgG. Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. ... View More
产品信息
MA564426
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K40073_16B3
抗原
Recombinant human ANKRD26P1 (aa 171-300).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 0.5% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HHANIESANK DELTPFLLAV HEQKQQMEDF LRKQKENLTA VKLESIHQVM SEYKENETPR NPQNSNPEGT SNKMACLGEG AAGAKVDEIP GNPVKRLFNK PSIDDSRPMS ANEDFDFDTE EKATEPANGK
Highest antigen sequence identity to the following orthologs: Mouse - 39%, Pig - 46%, Cynomolgus monkey - 95%.
靶标信息
ANKRD26P1 is a pseudogene closely related to the ANKRD26 gene, which is located on chromosome 10 and is characterized by having ankyrin repeat domains. The ANKRD26 gene plays a vital role in signal transduction and is implicated in hematological disorders, including inherited thrombocytopenia. This gene is involved in the regulation of type I cytokine receptor signaling, contributing to the maintenance of blood platelet levels and the immune response. Its mutations are associated with thrombocytopenia 2 (THC2), a condition marked by low platelet counts and an increased risk of developing hematologic malignancies. While ANKRD26 is actively transcribed and translated into a functional protein, ANKRD26P1, being a pseudogene, does not produce a protein product. Pseudogenes like ANKRD26P1 are sequences in the genome that resemble known genes but are typically non-functional due to mutations or lack of regulatory features necessary for expression. The presence of pseudogenes can still be biologically relevant, as they may play roles in gene regulation and evolution despite not encoding proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
Entrez Gene ID: (Human) 124149
