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Invitrogen
APC Polyclonal Antibody
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产品信息
PA5-16883
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide derived from C-terminus of human APC protein
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C
运输条件
Wet ice
产品详细信息
PA5-16883 targets APC (Adenomateous Polyposis Coli) in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-16883 immunogen is a synthetic peptide derived from C-terminus of human APC protein.
靶标信息
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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