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Invitrogen
APLF Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-57001
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SQLEGSTEIA KTQMTPTNSV SFLGENRDCN KQQPILAERK RILPTWMLAE HLSDQNLSVP AISGGNVIQG SGKEEICKDK SQLN
Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 48%.
靶标信息
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks.[supplied by OMIM, Mar 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; unnamed protein product; XRCC1-interacting protein 1; zinc finger, CX5CX6HX5H motif containing 1
基因别名: APFL; C2orf13; PALF; Xip1; ZCCHH1
UniProt ID: (Human) Q8IW19
Entrez Gene ID: (Human) 200558
nucleotide binding
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
protein binding
3'-5' exonuclease activity
histone binding
protein binding involved in protein folding
poly-ADP-D-ribose binding
histone chaperone activity
ADP-D-ribose modification-dependent protein binding
single strand break repair
DNA repair
regulation of DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
protein folding
cellular response to DNA damage stimulus
embryo implantation
regulation of epithelial to mesenchymal transition
protein localization to chromatin
DNA repair-dependent chromatin remodeling
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
