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Proteintech
APPBP1 Polyclonal Antibody
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产品信息
14863-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
APPBP1 Fusion Protein Ag6672 (181-534 aa encoded by BC000480)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EDLRLDKPF PELREHFQSY DLDHMEKKDH SHTPWIVIIA KYLAQWYSET NGRIPKTYKE KEDFRDLIRQ GILKNENGAP EDEENFEEAI KNVNTALNTT QIPSSIEDIF NDDRCINITK QTPSFWILAR ALKEFVAKEG QGNLPVRGTI PDMIADSGKY IKLQNVYREK AKKDAAAVGN HVAKLLQSIG QAPESISEKE LKLLCSNSAF LRVVRCRSLA EEYGLDTINK DEIISSMDNP DNEIVLYLML RAVDRFHKQQ GRYPGVSNYQ VEEDIGKLKS CLTGFLQEYG LSVMVKDDYV HEFCRYGAAE PHTIAAFLGG AAAQEVIKII TKQFVIFNNT YIYSGMSQTS ATFQL (181-534 aa encoded by BC000480)
靶标信息
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: amyloid beta precursor protein binding protein 1, 59kDa; Amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; Amyloid protein-binding protein 1; APP-BP1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; Proto-oncogene protein 1; protooncogene protein 1
基因别名: 59kDa; A-116A10.1; APPBP1; HPP1; NAE1; ula-1
UniProt ID: (Human) A8MU28, (Mouse) Q8VBW6
Entrez Gene ID: (Human) 8883, (Mouse) 234664, (Rat) 84019
