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Abnova
APPL2 Monoclonal Antibody (1C10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00055198-M06
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C10
抗原
APPL2 (NP_060641.2, 174 a.a. approximately 273 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: QHLSSLQYYC ALNALQYRKQ MAMMEPMIGF AHGQINFFKK GAEMFSKRMD SFLSSVADMV QSIQVELEAE AEKMRVSQQE LLSVDESVYT PDSDVAAPQI
靶标信息
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adapter protein containing PH domain, PTB domain and leucine zipper motif 2; adaptor protein; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; DIP13 beta; unnamed protein product
基因别名: DIP13B
UniProt ID: (Human) Q8NEU8
Entrez Gene ID: (Human) 55198
diet induced thermogenesis
protein import into nucleus
signal transduction
transforming growth factor beta receptor signaling pathway
cold acclimation
regulation of fibroblast migration
signaling
adiponectin-activated signaling pathway
regulation of toll-like receptor 4 signaling pathway
cellular response to hepatocyte growth factor stimulus
homeostatic process
glucose homeostasis
regulation of innate immune response
negative regulation of fatty acid oxidation
negative regulation of glucose import
negative regulation of neurogenesis
protein homotetramerization
positive regulation of phagocytosis, engulfment
positive regulation of cold-induced thermogenesis
negative regulation of cytokine production involved in inflammatory response
negative regulation of cellular response to insulin stimulus
positive regulation of macropinocytosis
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of G1/S transition of mitotic cell cycle
negative regulation of neural precursor cell proliferation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
