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Invitrogen
APRIL Polyclonal Antibody
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产品信息
PA1-29453
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide MPASSPFLLAPKGPPGN, corresponding to amino acids 1-17 of APRIL.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-29453 detects APRIL from human samples.
PA1-29453 has been successfully used in Western blot applications.
The PA1-29453 immunogen is: Synthetic peptide: MPASSPFLLAPKGPPGN, corresponding to amino acids 1-17 of APRIL.
靶标信息
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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