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Abnova
APTX Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00054840-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
APTX (NP_778242.1, 1 a.a. approximately 254 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVNELYPYIV EFEEEAKNPG LETHRKRKRS GNSDSIERDA AQEAEAGTGL EPGSNSGQCS VPLKKGKDAP IKKESLGHWS QGLKISMQDP KMQVYKDEQV VVIKDKYPKA RYHWLVLPWT SISSLKAVAR EHLELLKHMH TVGEKVIVDF AGSSKLRFRL GYHAIPSMSH VHLHVISQDF DSPCLKNKKH WNSFNTEYFL ESQAVIEMVQ EAGRVTVRDG MPELLKLPLR CHECQQLLPS IPQLKEHLRK HWTQ
靶标信息
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FHA-HIT; forkhead-associated domain histidine triad-like protein; major isoform; minor isoform; unnamed protein product
基因别名: AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
UniProt ID: (Human) Q7Z2E3
Entrez Gene ID: (Human) 54840
chromatin binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
double-stranded RNA binding
catalytic activity
protein binding
phosphoglycolate phosphatase activity
mismatched DNA binding
DNA 5'-adenosine monophosphate hydrolase activity
polynucleotide 3'-phosphatase activity
phosphoprotein binding
DNA-3'-diphospho-5'-guanosine diphosphatase
single-strand break-containing DNA binding
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
