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Invitrogen
ARFGAP1/ARFGAP3 Polyclonal Antibody
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ARFGAP1/ARFGAP3 Antibody (PA5-28707) in ICC/IF
ARFGAP1/ARFGAP3 Polyclonal Antibody detects ARFGAP3 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in -20°C 100% MeOH for 5 min. Green: ARFGAP3 protein stained by ARFGAP1/ARFGAP3 Polyclonal Antibody (Product # PA5-28707) diluted at 1:500. Blue: Hoechst 33343 staining.
产品信息
PA5-28707
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ARFGAP3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.42 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T.
Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase-activating protein 1; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 1; ARF GAP 3; ARF1 GAP; ARF1-directed GTPase-activating protein
基因别名: ARF1GAP; ARFGAP1; ARFGAP3; HRIHFB2281
UniProt ID: (Human) Q8N6T3, (Human) Q9NP61
Entrez Gene ID: (Human) 55738, (Human) 26286
