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Proteintech
ARFIP2 Polyclonal Antibody
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产品信息
14548-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ARFIP2 Fusion Protein Ag6076 (138-341 aa encoded by BC000392)
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RKYESVLQL GRALTAHLYS LLQTQHALGD AFADLSQKSP ELQEEFGYNA ETQKLLCKNG ETLLGAVNFF VSSINTLVTK TMEDTLMTVK QYEAARLEYD AYRTDLEELS LGPRDAGTRG RLESAQATFQ AHRDKYEKLR GDVAIKLKFL EENKIKVMHK QLLLFHNAVS AYFAGNQKQL EQTLQQFNIK LRPPGAEKPS WLEEQ (138-341 aa encoded by BC000392)
靶标信息
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR1
基因别名: 2310002N04Rik; ARFIP2; POR; POR1
UniProt ID: (Human) P53365, (Rat) Q6AY65, (Mouse) Q8K221
Entrez Gene ID: (Human) 23647, (Rat) 293344, (Mouse) 76932
