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Invitrogen
ARHGAP22 Polyclonal Antibody
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产品信息
PA5-36510
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 564-620 of human ARHGAP22
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous protein at a molecular weight of 77 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm, and contains one Rho-GAP domain and one PH domain. ARHGAP22 functions as a GTPase-activating protein for Rac 1 converting it to an inactive GDP-bound state and, through its interaction with ZNF161 (VEZF1), is thought to be useful in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p68RacGAP; RHG22; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22
基因别名: ARHGAP22; B230341L19Rik; p68RacGAP; RHOGAP2; RhoGap22
UniProt ID: (Human) Q7Z5H3, (Mouse) Q8BL80
Entrez Gene ID: (Human) 58504, (Mouse) 239027, (Rat) 306279
