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Invitrogen
ARPP19 Polyclonal Antibody
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产品信息
PA5-68127
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human ARPP19 (aa 6-25).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Human and Rat samples.
靶标信息
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARPP-19; cAMP regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein ARPP-19; cAMP-regulated phosphoprotein, 19kDa; cyclic AMP phosphoprotein, 19 kD; cyclic AMP phosphoprotein, 19 kDa; cyclic AMP phosphoprotein, 19kD
基因别名: 19kDa; 2700024H10Rik; ARPP-16; ARPP-19; Arpp12; ARPP16; ARPP19; AW559096; ENSAL
UniProt ID: (Human) P56211, (Mouse) P56212, (Rat) Q712U5
Entrez Gene ID: (Human) 10776, (Mouse) 59046, (Rat) 60336
G2/M transition of mitotic cell cycle
cell cycle
mitotic nuclear division
positive regulation of gluconeogenesis
positive regulation of Ras protein signal transduction
cell division
dopamine receptor signaling pathway
negative regulation of catalytic activity
regulation of catalytic activity
regulation of protein phosphatase type 2A activity
positive regulation of glucose import
