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Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATPase family AAA domain-containing protein 5; ATPase family, AAA domain containing 5; chromosome fragility associated gene 1; Chromosome fragility-associated gene 1 protein; enhanced level of genomic instability 1 homolog; FLJ12735
基因别名: ATAD5; C130052G03Rik; C17orf41; ELG1; FRAG1; Gm17; RGD1561464
UniProt ID: (Human) Q96QE3, (Mouse) Q4QY64
Entrez Gene ID: (Human) 79915, (Mouse) 237877, (Rat) 303348