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Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation (By similarity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Autophagy-related protein 32; ECM17; Extracellular mutant protein 37
基因别名: ATG32; ECM17; ECM37; YIL146C
UniProt ID: (Baker's yeast) P40458
Entrez Gene ID: (Baker's yeast) 854660