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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Additional Information: This antibody is expected to recognize all reported isoforms (NP_004037.1; NP_001244263.1; NP_001001935.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
The ATP5F1A gene (ATP Synthase F1 Subunit Alpha) is located on chromosome 18q21.33 and encodes a critical component of the mitochondrial ATP synthase complex, specifically the F1 catalytic core. The ATP synthase complex is essential for cellular energy production, facilitating the conversion of ADP to ATP during oxidative phosphorylation. The ATP5F1A subunit is responsible for the catalysis of ATP synthesis driven by the proton gradient across the inner mitochondrial membrane. Dysfunctions or mutations in ATP5F1A can result in mitochondrial disorders and are linked to various metabolic and neurodegenerative diseases. Understanding the structure and function of ATP5F1A is vital for comprehending the bioenergetics of cellular respiration and has implications in studying mitochondrial pathologies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP synthase alpha chain, mitochondrial; ATP synthase alpha subunit precursor (EC 3.6.1.3); ATP synthase subunit alpha heart isoform, mitochondrial; ATP synthase subunit alpha liver isoform, mitochondrial; ATP synthase subunit alpha, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; ATP sythase (F1-ATPase) alpha subunit; cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1; epididymis secretory sperm binding protein Li 123m; iso; mitochondrial ATP synthetase, oligomycin-resistant; mitochondrial H+-ATP synthase alpha subunit; modifier of Min 2; unnamed protein product
基因别名: ATP5A; ATP5A1; ATP5A2; ATP5AL2; ATPM; COXPD22; D18Ertd206e; hATP1; HEL-S-123m; MC5DN4; MC5DN4A; MC5DN4B; MOM2; OMR; ORM
UniProt ID: (Human) P25705, (Pig) P80021, (Rat) P15999, (Mouse) Q03265
Entrez Gene ID: (Human) 498, (Pig) 100157880, (Rat) 65262, (Mouse) 11946