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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SILEERILGA DTSVDLEETG RVLSIGDGIA RVHGLRNVQA EEMVEFSSGL KGMSLNLEPD NVGVVVFGND KLIKEGDIVK RTGAIVDVPV GEELLGRVVD
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 99%.
The ATP5F1A gene (ATP Synthase F1 Subunit Alpha) is located on chromosome 18q21.33 and encodes a critical component of the mitochondrial ATP synthase complex, specifically the F1 catalytic core. The ATP synthase complex is essential for cellular energy production, facilitating the conversion of ADP to ATP during oxidative phosphorylation. The ATP5F1A subunit is responsible for the catalysis of ATP synthesis driven by the proton gradient across the inner mitochondrial membrane. Dysfunctions or mutations in ATP5F1A can result in mitochondrial disorders and are linked to various metabolic and neurodegenerative diseases. Understanding the structure and function of ATP5F1A is vital for comprehending the bioenergetics of cellular respiration and has implications in studying mitochondrial pathologies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP synthase F(1) complex subunit alpha, mitochondrial; ATP synthase F1 subunit alpha; iso
基因别名: ATP5A; ATP5A1; ATP5AL2; ATP5F1A; ATPM
Entrez Gene ID: (Human) 498