Invitrogen

ATP6V0C Polyclonal Antibody

Name: ATP6V0C Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-23972
Availability: InStock

2 篇参考文献

查看其他5个ATP6V0C抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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ATP6V0C Antibody (PA5-23972) in WB

Western blot analysis of ATP6V0C in mouse NIH-3T3 cell line lysates. Samples were incubated with ATP6V0C polyclonal antibody (Product # PA5-23972). Lysates: 35 µg/lane. ATP6V0C protein (arrow).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image ATP6V0C Polyclonal Antibody

产品信息

PA5-23972

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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Proximity Ligation Assay (PLA) (PLA)

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产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 100-126 amino acids from the C-terminal region of human ATP6V0C

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

800 µg

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2541472

产品详细信息

This antibody is predicted to react with bovine, canine, equine and rat based on sequence homology.

靶标信息

ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. ATP6V0C encodes the V0 subunit c.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: ATP6V0C; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa; ATPase, H+ transporting, lysosomal 16kD, V0 subunit C; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c; ATPase, H+ transporting, lysosomal 2; H(+)-ATPase (mvp); H(+)-transporting two-sector ATPase, 16 kDa subunit; PL16; V-ATPase 16 kDa proteolipid subunit; V-ATPase 16 kDa proteolipid subunit c; V-type proton ATPase 16 kDa proteolipid subunit; V-type proton ATPase 16 kDa proteolipid subunit c; vacuolar ATP synthase 16 kDa proteolipid subunit; vacuolar H+ ATPase proton channel subunit; vacuolar proton pump 16 kDa proteolipid subunit; Vacuolar proton pump 16 kDa proteolipid subunit c

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基因别名: ATP6C; Atp6c2; ATP6L; ATP6V0C; ATPL; Atpl-rs1; EPEO3; Mvp; PL16; VATL; Vma3; VPPC

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UniProt ID: (Mouse) P63082

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Entrez Gene ID: (Human) 527, (Mouse) 11984

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功能

protein binding hydrogen ion transmembrane transporter activity ubiquitin protein ligase binding proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism guanyl nucleotide exchange factor activator activity hydrogen-exporting ATPase activity, phosphorylative mechanism ATP synthase

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