Proteintech

AVEN Polyclonal Antibody

Name: AVEN Polyclonal Antibody
Brand: Proteintech
SKU: 25846-1-AP
Price: ... USD
Availability: InStock

2 篇参考文献

查看其他11个AVEN抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

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抗体检测数据 (2)

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AVEN Antibody (25846-1-AP) in WB

MCF-7 cells were subjected to SDS PAGE followed by western blot with 25846-1-AP ( AVEN Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image AVEN Polyclonal Antibody

产品信息

25846-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

AVEN Fusion Protein Ag23020 (1-362 aa encoded by BC010488)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.38 mg/mL

57 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MQAERGARG GRGRRPGRGR PGGDRHSERP GAAAAVARGG GGGGGGDGGG RRGRGRGRGF RGARGGRGGG GAPRGSRREP GGWGAGASAP VEDDSDAETY GEENDEQGNY SKRKIVSNWD RYQDIEKEVN NESGESQRGT DFSVLLSSAG DSFSQFRFAE EKEWDSEASC PKQNSAFYVD SELLVRALQE LPLCLRLNVA AELVQGTVPL EVPQVKPKRT DDGKGLGMQL KGPLGPGGRG PIFELKSVAA GCPVLLGKDN PSPGPSRDSQ KPTSPLQSAG DHLEEELDLL LNLDAPIKEG DNILPDQTSQ DLKSKEDGEV VQEEEVCAKP SVTEEKNMEP EQPSTSKNVT EEELEDWLDS MIS (1-362 aa encoded by BC010488)

靶标信息

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。