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Invitrogen
AZIN1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-82991
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AKVGVNILTC DNEIELKKIA RNHPNAKVLL HIATEDNIGG EEGNMKFGTT LKNCRHLLEC AKELDVQIIG VKFHVSSACK ESQVYV
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 94%.
靶标信息
Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: O OAZIN; OAZIN; ornithine decarboxylase antizyme inhibitor; similar to Homo sapiens antizyme inhibitor encoded by GenBank Accession Number D88674; unnamed protein product
基因别名: AZI; AZI1; AZIA1; OAZI; OAZIN; ODC1L
UniProt ID: (Human) O14977
Entrez Gene ID: (Human) 51582
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