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Invitrogen
Acinus Polyclonal Antibody
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产品信息
PA1-12496
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide (TRTALHGVKWPQSNPK) corresponding to aa 1065-1080 of human AcinusL, 338-353 of human AcinusS' or 307-322 of human AcinusS. Sequence is located near the C-terminus of the cleaved active peptide p17.
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
A suggested positive control for this product is K562 cell lysate.
靶标信息
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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