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Invitrogen
Adenylate Cyclase 8 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-55041
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DRRNSGATFT EGSWSPELPF DNIVGKQNTL AALTRNSINL LPNHLAQALH VQSGPEEINK RIEHTIDLRS GDKLRREHIK PFSLMF
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adenylate cyclase 8 (brain); adenylate cyclase type VIII; adenylyl cyclase 8; adenylyl cyclase-8, brain; ATP pyrophosphate-lyase 8; ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP; HEL-S-172mP
基因别名: AC8; ADCY3; HBAC1
UniProt ID: (Human) P40145
Entrez Gene ID: (Human) 114
system process
renal water homeostasis
cAMP biosynthetic process
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
learning or memory
memory
locomotory behavior
cyclic nucleotide biosynthetic process
glucose mediated signaling pathway
positive regulation of synaptic plasticity
positive regulation of insulin secretion
activation of protein kinase A activity
intracellular signal transduction
positive regulation of insulin secretion involved in cellular response to glucose stimulus
opioid receptor signaling pathway
glucose homeostasis
chemical homeostasis
protein oligomerization
protein homooligomerization
regulation of cytosolic calcium ion concentration
cellular response to calcium ion
cellular response to morphine
cellular response to glucose stimulus
cellular response to glucagon stimulus
regulation of cellular response to stress
vascular endothelial cell response to laminar fluid shear stress
neuroinflammatory response
positive regulation of long-term synaptic potentiation
positive regulation of long term synaptic depression
cellular response to forskolin
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