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Invitrogen
Albendazole I Recombinant Mouse Monoclonal Antibody (2H3)
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Albendazole I Antibody (MA566569) in SDS-PAGE
SDS-PAGE characterization of Albendazole I under reducing conditions. Lane M: Protein marker (kDa); Lane ABZ: Purified Albendazole I Recombinant Monoclonal (Product # MA566569). Albendazole I showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-415.
产品信息
MA566569
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2H3
抗原
Conjugate of ABZ hapten and KLH.
偶联物
形式
Liquid
浓度
9.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Albendazole is a benzimidazole derivative that acts as a broad-spectrum anthelmintic, primarily used in the treatment of parasitic worm infestations, including those caused by roundworms, tapeworms, and flukes. Structurally, albendazole is characterized by a benzimidazole ring fused to a thiazole moiety, which enables its mode of action by binding to and inhibiting tubulin polymerization, thus preventing microtubule formation in the intestinal cells of parasites. This disruption impairs glucose uptake, leading to energy depletion and eventual parasite death. Albendazole is administered orally and is effective against a wide range of intestinal and tissue parasites, making it a critical component of mass deworming programs globally. While typically well-tolerated, potential side effects can include liver function alterations, necessitating monitoring in long-term use. Ongoing research explores its efficacy in combination therapies and potential applications in treating emerging parasitic diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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