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Biologo
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Reconstitute with 0.5 mL sterile water to get a stock solution of 200 µg/mL.
Positive control: Infected skin or oral mucosa.
Reactivity: Human and other primates (no reactivity in chicken, cat, rabbit, rat, sheep and goat).
Human alpha-defensins (HNP1-3) are synthesized and stored by neutrophilic granulocytes. Human defensins are Cys-rich antimicrobial peptides which specifically react against Gram-negative bacteria. Originally defensins were isolated from hemolysates, but they can also be found on the cell surface of epithelia of the urogenital tract, lung, and trachea. In leukocytes defensins are stored in granules being released into phagolysosomes for the destruction of incorporated microorganisms. Amino acid sequences of alpha-defensins 1-4 (HNP1-4) and beta-Defensins 1-4 (HBD1-4) are known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。