Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Angiocidin Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
PA5-149025
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse S5a/Angiocidin isoform A, Val2-Glu254
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Angiocidin, also known as thrombospondin-1 (TSP-1), is a multifunctional protein encoded by the THBS1 gene. It plays a critical role in various physiological and pathological processes, including angiogenesis, wound healing, and tumor progression. As an anti-angiogenic factor, angiocidin inhibits the formation of new blood vessels by binding to and regulating the activity of several cell surface receptors, such as CD36 and integrins. This function is crucial in maintaining tissue homeostasis and preventing the uncontrolled growth of blood vessels, which is a hallmark of cancer. Angiocidin also modulates cell adhesion, migration, and apoptosis, contributing to its role in tissue repair and immune response regulation. Elevated levels of angiocidin have been observed in various cancers, where it can influence tumor growth and metastasis. Additionally, it has been implicated in other diseases characterized by abnormal angiogenesis and inflammation, such as diabetic retinopathy and rheumatoid arthritis. Understanding the regulation and function of angiocidin is essential for developing therapeutic strategies aimed at modulating its activity to treat cancer and other angiogenesis-related diseases. Research into angiocidin offers valuable insights into its potential as a therapeutic target and biomarker for disease diagnosis and prognosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
