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NeoBiotechnologies
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody is tested in direct ELISA.
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: angiotensin converting enzyme precursor (EC 3.4.15.1); angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I-converting enzyme; angiotensin I-converting enzyme precursor (EC 3.4.15.1); carboxycathepsin; CD143 antigen; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; kininase II; MGC26566; peptidase P; unnamed protein product; Zn2+ carboxydipeptidase enzyme which transforms angiotensin I into angiotensin II an active vasoconstrictor protein; splice-site mutation IVS25+1G-->A leads to the retention of intron 25 resulting in a frameshift which leads to a premature stop codon
基因别名: ACE1; CD143; DCP; DCP1
UniProt ID: (Human) P12821
Entrez Gene ID: (Human) 1636