Search
Additional Information:
{{banner.description}}
图: 1 / 3
Annexin A1 Antibody (711089) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of K-562 (Lane 1), A549 (Lane 2), U-87 MG (Lane 3), MOLT4 (Lane 4), THP-1 (Lane 5), U-937 (Lane 6), RAW 264.7 (Lane 7), A-431 (Lane 8) and Mouse Lung (Lane 9). The blots were probed with Anti-Annexin A1 Recombinant Rabbit Superclonal™ Antibody (Product # 711089, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 38 kDa band corresponding... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
711089
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
抗原
Protein corresponding to Human ANXA1 (aa 33-346)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2-7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Monkey, Sheep and Pig
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
靶标信息
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ANAX1; Annexin A1; Annexin I; Annexin-1; ANX1; Calpactin II; Calpactin-2; Chromobindin-9; epididymis secretory sperm binding protein; lipocortin 1; Lipocortin I; LPC1; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1
基因别名: Anx-1; Anx-A1; ANX1; ANXA1; C430014K04Rik; Lpc-1; LPC1
UniProt ID: (Mouse) P10107
Entrez Gene ID: (Mouse) 16952
single-stranded DNA binding
single-stranded RNA binding
helicase activity
phospholipase inhibitor activity
structural molecule activity
calcium ion binding
protein binding
phospholipid binding
calcium-dependent phospholipid binding
phospholipase A2 inhibitor activity
protein binding, bridging
double-stranded DNA-dependent ATPase activity
annealing helicase activity
protein homodimerization activity
calcium-dependent protein binding
calcium-binding protein
DNA strand renaturation
neutrophil homeostasis
signal transduction
cell surface receptor signaling pathway
peptide cross-linking
insulin secretion
keratinocyte differentiation
positive regulation of vesicle fusion
positive regulation of prostaglandin biosynthetic process
DNA duplex unwinding
positive regulation of neutrophil apoptotic process
DNA rewinding
regulation of cell proliferation
positive regulation of apoptotic process
alpha-beta T cell differentiation
arachidonic acid secretion
negative regulation of protein secretion
cellular response to hydrogen peroxide
prolactin secretion
cellular response to glucocorticoid stimulus
neutrophil clearance
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of phospholipase A2 activity
negative regulation of interleukin-8 secretion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
