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Invitrogen
Arfaptin 2 Polyclonal Antibody
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产品信息
PA1-27827
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human Arfaptin-2.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-27827 detects ARFIP2 from human, mouse, and rat samples.
PA1-27827 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27689 immunogen is a synthetic peptide corresponding to human Arfaptin-2.
靶标信息
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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