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Invitrogen
Aspirin Recombinant Mouse Monoclonal Antibody (2C11)
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Aspirin Antibody (MA566631) in SDS-PAGE
SDS-PAGE characterization of Aspirin under reducing conditions. Lane M: Protein marker (kDa); Lane ASP: Purified Aspirin Recombinant Monoclonal (Product # MA566631). Aspirin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-351.
产品信息
MA566631
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2C11
抗原
Conjugate of ASA hapten and KLH.
偶联物
形式
Liquid
浓度
5.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Aspirin, a widely used analgesic and anti-inflammatory agent, is primarily known for its role in preventing major adverse cardiovascular events (MACE). It functions by irreversibly inhibiting the cyclooxygenase (COX) enzyme, leading to decreased synthesis of prostaglandins and thromboxanes, which are involved in inflammation and platelet aggregation. Aspirin is synthesized from salicylic acid and is often administered in various formulations, including enteric-coated tablets to minimize gastrointestinal side effects. The bioavailability of aspirin can vary based on formulation and whether it is taken with food, as food can interfere with absorption, particularly in enteric-coated forms. Recent studies have questioned the universal applicability of aspirin guidelines, suggesting that personalized approaches may be necessary for optimal cardiovascular protection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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