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Proteintech
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Immunogen sequence: CKVQEQPPA IPEALAWPTP PTRPAPAPCH ANTSMVTHPD FATQPQHVQN FLLYRHYRHF PLLQDVPPSK CAQPVFLLLV IKSSPSNYVR RELLRRTWGR ERKVRGLQLR LLFLVGTASN PHEARKVNRL LELEAQTHGD ILQWDFHDSF FNLTLKQVLF LQWQETRCAN ASFVLNGDDD VFAHTDNMVF YLQDHDPGRH LFVGQLIQNV GPIRAFWSKY YVPEVVTQNE RYPPYCGGGG FLLSRFTAAA LRRAAHVLDI FPIDDVFLGM CLELEGLKPA SHSGIRTSGV RAPSQHLSSF DPCFYRDLLL VHRFLPYEML LMWDALNQPN LTCGNQTQIY (34-372 aa encoded by BC066876)
This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; Beta-1,3-galactosyltransferase 8; Beta-1,3-GalTase 8; beta-1,3-Gn-T3; beta-1,3-N-acetylglucosaminyltransferase 3; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; Beta-3-Gx-T8; beta3GalT8; beta3Gn-T3; BGnT-3; core 1 beta-1,3-N-acetylglucosaminyltransferase; Core 1 extending beta-1,3-N-acetylglucosaminyltransferase; Core1-beta3GlcNAcT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; putative type II membrane protein; Transmembrane protein 3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
基因别名: 2210008L19Rik; B3GAL-T8; B3GALT8; B3GN-T3; B3GNT-3; B3GNT3; beta3Gn-T3; HP10328; TMEM3; UNQ637/PRO1266
UniProt ID: (Human) Q9Y2A9, (Mouse) Q5JCS9
Entrez Gene ID: (Human) 10331, (Mouse) 72297