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Invitrogen
BAP31 Monoclonal Antibody (297-D4)
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产品信息
MA5-33223
产品规格
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
297-D4
抗原
Differentiated and undifferentited human embryonic stem cells
偶联物
形式
Liquid
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
RRID
靶标信息
BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo- and hetero-oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL-2/BCL-XL-associated protein. In the C-terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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